diff --git a/lib/Kconfig.debug b/lib/Kconfig.debug
index 646778e68f00..1699b2124558 100644
--- a/lib/Kconfig.debug
+++ b/lib/Kconfig.debug
@@ -208,6 +208,11 @@ config DEBUG_BUGVERBOSE
 
 endmenu # "printk and dmesg options"
 
+# Clang is known to generate .{s,u}leb128 with symbol deltas with DWARF5, which
+# some targets may not support: https://sourceware.org/bugzilla/show_bug.cgi?id=27215
+config AS_HAS_NON_CONST_LEB128
+	def_bool $(as-instr,.uleb128 .Lexpr_end4 - .Lexpr_start3\n.Lexpr_start3:\n.Lexpr_end4:)
+
 menu "Compile-time checks and compiler options"
 
 config DEBUG_INFO
@@ -274,7 +279,7 @@ choice
 
 config DEBUG_INFO_DWARF_TOOLCHAIN_DEFAULT
 	bool "Rely on the toolchain's implicit default DWARF version"
-	depends on !CC_IS_CLANG || AS_IS_LLVM || CLANG_VERSION < 140000 || (AS_IS_GNU && AS_VERSION >= 23502)
+	depends on !CC_IS_CLANG || AS_IS_LLVM || CLANG_VERSION < 140000 || (AS_IS_GNU && AS_VERSION >= 23502 && AS_HAS_NON_CONST_LEB128)
 	help
 	  The implicit default version of DWARF debug info produced by a
 	  toolchain changes over time.
@@ -296,7 +301,7 @@ config DEBUG_INFO_DWARF4
 
 config DEBUG_INFO_DWARF5
 	bool "Generate DWARF Version 5 debuginfo"
-	depends on !CC_IS_CLANG || AS_IS_LLVM || (AS_IS_GNU && AS_VERSION >= 23502)
+	depends on !CC_IS_CLANG || AS_IS_LLVM || (AS_IS_GNU && AS_VERSION >= 23502 && AS_HAS_NON_CONST_LEB128)
 	depends on !DEBUG_INFO_BTF
 	help
 	  Generate DWARF v5 debug info. Requires binutils 2.35.2, gcc 5.0+ (gcc