diff --git a/drivers/iio/imu/inv_icm42600/inv_icm42600_i2c.c b/drivers/iio/imu/inv_icm42600/inv_icm42600_i2c.c
index 85b1934cec60..53891010a91d 100644
--- a/drivers/iio/imu/inv_icm42600/inv_icm42600_i2c.c
+++ b/drivers/iio/imu/inv_icm42600/inv_icm42600_i2c.c
@@ -18,12 +18,15 @@ static int inv_icm42600_i2c_bus_setup(struct inv_icm42600_state *st)
 	unsigned int mask, val;
 	int ret;
 
-	/* setup interface registers */
-	ret = regmap_update_bits(st->map, INV_ICM42600_REG_INTF_CONFIG6,
-				 INV_ICM42600_INTF_CONFIG6_MASK,
-				 INV_ICM42600_INTF_CONFIG6_I3C_EN);
-	if (ret)
-		return ret;
+	/*
+	 * setup interface registers
+	 * This register write to REG_INTF_CONFIG6 enables a spike filter that
+	 * is impacting the line and can prevent the I2C ACK to be seen by the
+	 * controller. So we don't test the return value.
+	 */
+	regmap_update_bits(st->map, INV_ICM42600_REG_INTF_CONFIG6,
+			   INV_ICM42600_INTF_CONFIG6_MASK,
+			   INV_ICM42600_INTF_CONFIG6_I3C_EN);
 
 	ret = regmap_update_bits(st->map, INV_ICM42600_REG_INTF_CONFIG4,
 				 INV_ICM42600_INTF_CONFIG4_I3C_BUS_ONLY, 0);