diff --git a/src/qemu/qemu_hotplug.c b/src/qemu/qemu_hotplug.c
index d33fc87c51..e69c1a031e 100644
--- a/src/qemu/qemu_hotplug.c
+++ b/src/qemu/qemu_hotplug.c
@@ -1157,6 +1157,30 @@ static inline int qemuFindDisk(virDomainDefPtr def, const char *dst)
     return -1;
 }
 
+static int qemuComparePCIDevice(virDomainDefPtr def ATTRIBUTE_UNUSED,
+                                virDomainDeviceInfoPtr dev1,
+                                void *opaque)
+{
+    virDomainDeviceInfoPtr dev2 = opaque;
+
+    if (dev1->type !=  VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI ||
+        dev2->type != VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI)
+        return 0;
+
+    if (dev1->addr.pci.slot == dev2->addr.pci.slot &&
+        dev1->addr.pci.function != dev2->addr.pci.function)
+        return -1;
+    return 0;
+}
+
+static bool qemuIsMultiFunctionDevice(virDomainDefPtr def,
+                                      virDomainDeviceInfoPtr dev)
+{
+    if (virDomainDeviceInfoIterate(def, qemuComparePCIDevice, dev) < 0)
+        return true;
+    return false;
+}
+
 
 int qemuDomainDetachPciDiskDevice(struct qemud_driver *driver,
                                   virDomainObjPtr vm,
@@ -1178,6 +1202,13 @@ int qemuDomainDetachPciDiskDevice(struct qemud_driver *driver,
 
     detach = vm->def->disks[i];
 
+    if (qemuIsMultiFunctionDevice(vm->def, &detach->info)) {
+        qemuReportError(VIR_ERR_OPERATION_FAILED,
+                        _("cannot hot unplug multifunction PCI device: %s"),
+                        dev->data.disk->dst);
+        goto cleanup;
+    }
+
     if (qemuCgroupControllerActive(driver, VIR_CGROUP_CONTROLLER_DEVICES)) {
         if (virCgroupForDomain(driver->cgroup, vm->def->name, &cgroup, 0) != 0) {
             qemuReportError(VIR_ERR_INTERNAL_ERROR,
@@ -1417,6 +1448,13 @@ int qemuDomainDetachPciControllerDevice(struct qemud_driver *driver,
         goto cleanup;
     }
 
+    if (qemuIsMultiFunctionDevice(vm->def, &detach->info)) {
+        qemuReportError(VIR_ERR_OPERATION_FAILED,
+                        _("cannot hot unplug multifunction PCI device: %s"),
+                        dev->data.disk->dst);
+        goto cleanup;
+    }
+
     if (qemuDomainControllerIsBusy(vm, detach)) {
         qemuReportError(VIR_ERR_OPERATION_FAILED, "%s",
                         _("device cannot be detached: device is busy"));
@@ -1504,6 +1542,13 @@ int qemuDomainDetachNetDevice(struct qemud_driver *driver,
         goto cleanup;
     }
 
+    if (qemuIsMultiFunctionDevice(vm->def, &detach->info)) {
+        qemuReportError(VIR_ERR_OPERATION_FAILED,
+                        _("cannot hot unplug multifunction PCI device :%s"),
+                        dev->data.disk->dst);
+        goto cleanup;
+    }
+
     if ((vlan = qemuDomainNetVLAN(detach)) < 0) {
         qemuReportError(VIR_ERR_OPERATION_FAILED,
                         "%s", _("unable to determine original VLAN"));
@@ -1633,6 +1678,13 @@ int qemuDomainDetachHostPciDevice(struct qemud_driver *driver,
         return -1;
     }
 
+    if (qemuIsMultiFunctionDevice(vm->def, &detach->info)) {
+        qemuReportError(VIR_ERR_OPERATION_FAILED,
+                        _("cannot hot unplug multifunction PCI device: %s"),
+                        dev->data.disk->dst);
+        return -1;
+    }
+
     if (!virDomainDeviceAddressIsValid(&detach->info,
                                        VIR_DOMAIN_DEVICE_ADDRESS_TYPE_PCI)) {
         qemuReportError(VIR_ERR_OPERATION_FAILED,